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Melvin Druelinger Ph.D.

Professor Organic Chemistry

Melvin Druelinger Ph.D.
Contact Info
Chemistry (CHEM) 214


Ph.D. University of Wisconsin (Madison) - Physical Organic Chemistry (D. Lemal)

B.S.  Indiana University (Bloomington) – Chemistry

NSF Program Director (academic rotator)

DowElanco - Senior Research Chemist and Organofluorine Consultant

U.S. Air Force Academy – University Resident Research Fellow, F. J.

Seiler Research Laboratory

Colorado State University – Postdoctoral Research Associate (A.I. Meyers)

Iowa State University – Postdoctoral Fellow (Orville Chapman)

Research Interests

Organic synthesis, organofluorine chemistry, heterocycles (especially tetrazines), cycloadditions, highly reactive intermediates, polymers, small ring systems (polyheterocyclic, strained), photochemistry

Teaching Interests:                   

Organic chemistry, synthesis, mechanisms, heterocycles, cycloadditions, spectroscopy, polymers, photochemistry, chemical education

Teaches: Organic Chemistry I and II lectures and labs, Advanced Organic Chemistry (lecture and labs), Spectroscopy

Other Activities

Current projects:

Electrophilic fluorinations of alkenes (fluoroamides and fluoroamines)
Electrophilic fluorination of aromatics
Cycloadditions of tetrazines
Synthesis of novel tetrazine polymers


N. Jaksic, M. Druelinger and L. Mandicello, "Industrial Hemp as a Reinforcing Agent in 3D-printing PLA Filament Composites, to be submitted to the Journal of Cannabis Research, spring 2018.

M. Druelinger, D. Dillon and S. Schelble, “Preparation of Tetrazines: A Research DerivedUndergraduate Research Prototype for Upper Division Organic Chemistry Labs, J. of Chemical Education, collaborative manuscript in preparation.

M. Druelinger, “ Starting a Successful Research Program at a Predominantly UndergraduateInstitution”, 247th National American Chemical Society Meeting, Dallas, TX, March 25,2014, invited presentation as part of a symposium “Starting a Successful Research Program at a Predominantly Undergraduate Institution, available from ACS On Demand at

M. Druelinger, “Responsible Conduct of Research: Is This an Issue for Undergraduate Research? A View from the Trenches”, Invited Plenary lecture, CUR Dialogues, 2011, posted at

N. Jaksic, J. Piquette, M. Druelinger, et al.,”Maturing of a Multidisciplinary Cohort of STEM Scholars: Year Three”, 2010 ASEE Proceedings  - Zone IV Conference, 121-131, (2010) – a peer reviewed paper.

N. Jaksic, K. Sinkhorn, M. Druelinger, et al., “Multidisciplinary Cohorts of STEM Scholars:Challenges and Rewards”, Proceedings of the 2009 ASEE Rocky Mountain Section Annual Conference, (2009) – a peer reviewed paper.

A.M. Schoffstall, B.A. Gaddis and M.L. Druelinger, Microscale and Miniscale Organic Chemistry Laboratory Experiments, 2nd Edition, McGraw-Hill, Boston, 675 pages, 2004, ISBN 0-07-294338-6.

D. Shellhamer, R. Chapman, M. Druelinger and R. Callahan*, "Facile Addition of Poorly Nucleophilic Alcohols to Unactivated Alkenes", Synthesis, 1056, (1997).

M. Druelinger, R. Chapman, D. Shellhamer and M. Riner*, "Addition Reactions of Alkenes with Electronegatively Substituted Alcohols in the Presence of Xenon Difluoride", J. Chem. Soc. (London), Perkin Transactions II, 787, (1997).

D.F. Shellhamer, S.L. Carter*, R.H. Dunham*, S.N. Graham*, V.L. Heasley, R.D. Chapman and M.L. Druelinger, "Regioselectivity in the Addition Reactions of   Alkoxyxenonfluorides with Indene," Journal of the Chemical Society (London) Perkin Transactions II, 159 (1989).

J.S. Wilkes, J.A. Levisky, M.L. Druelinger and C.L. Hussey, "Dialkylimidazolium Chloroaluminate Molten Salts", Proceedings of the Third International Symposium on Molten Salts, (The Electrochemical Society), 11 pages, Vol 81-9, 245 (1982).

R.A. Hildreth, M.L. Druelinger and S.A. Shackelford, "Xenon Difluoride Fluorination.  IV. Photochemically Initiated Xenon Difluoride Fluorination of Norbornene", Tetrahedron Letters, 23, 1059 (1982).

A.I. Meyers, D.R. Williams, G.W. Erickson, S. White and M.L. Druelinger,    "Enantioselective Alkylation of Ketones via Chiral, Nonracemic Lithioenamines.  An Asymmetric Synthesis of α-Alkyl and α,α'-Dialkyl Cyclic Ketones", Journal of the American Chemical Society, 103, 3081 (1981).



N. Jaksic and M. Druelinger, “Industrial Hemp Fibers as Reinforcing Agents in 3-D Printing Filament Composites”, 2017 Institute for Cannabis Research Conference, Pueblo, CO, April 29, 2017.

M. Druelinger and A. Trimble*, “Microwave Synthesis of β-Fluoroamides from  Alkenes“, 253rd National ACS Meeting, San Francisco, CA, April 2, 2017.

M. Druelinger, “The Art and Necessity of Gaining Internal Support from Institutional Administrators”, 253rd National ACS Meeting, San Francisco, CA, April 1, 2017 (presenter, chair and organizer, part of a symposium).

A. Schoffstall and M. Druelinger, “Tracing the Changing Content of Organic Chemistry”, ACS Rocky Mountain Regional meeting, Loveland, CO, October 26, 2017.

J. Garcia, M. Druelinger and D. Dillon, “Developing Electrophilic Fluorination Experiments for the Undergraduate Organic Laboratory”, ACS Rocky Mountain Regional meeting, Loveland, CO, October 27, 2017.

M. Druelinger and M. Castellani, “How to Get Started in Research in the Natural Sciences with Undergraduates”, Workshop, CUR National Conference, Tampa, FL, June 25, 2016.

J. Mutz and M. Druelinger, “Synthesis of β-Fluoroamines”, 249th National ACS Meeting, Denver, CO, April, 2015.

S.G. Williams and M. Druelinger, “Synthesis of a Bisphenolic Tetrazine from Cyanophenols and Subsequent Conversion to Pyridazines and Polyesters”, 247th National ACS Meeting, Dallas, TX, March, 2014.

M. Druelinger, S. Schelble and D. Dillon, “Examination of the Inverse Electron-Demand Character of the Diels-Alder Reaction of Tetrazines, both Experimentally and Computationally Using a Frontier Orbital Analysis”, Rocky Mountain Regional Meeting of the ACS, Westminster, CO, October 20, 2014.

J. P. Yapor and M. Druelinger, “Fluorination of Alkenes with SelectfluorTM to Form  β-Fluoroamides and Amines”, 245th National ACS Meeting, New Orleans, LA, March 2013.

M. Druelinger, S. Schelble and D. Dillon, “Preparation of Tetrazines: Undergraduate Research for Teaching about Pericyclic Reactions”, Advances in Organic Teaching Symposium, 244th National ACS Meeting, Philadelphia, PA, August 20, 2012 (Invited)

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